You should report any side effects that are not listed in the patient information leaflet to your doctor. In the case of type 1 diabetes this is likely unless research finds an alternative treatment. It is not so uncommon for people with type 2 diabetes to come off medication. This is particularly a possibility for people who have successfully lost a lot of weight.

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Another non-insulin injection for people with diabetes is exenatide (Byetta). This medication, originally derived from a compound found in the saliva of the Gila monster, triggers insulin release from the pancreas when blood glucose levels rise. Exenatide is meant to be used along with oral diabetes drugs. It is dosed twice daily and should be injected within an hour of the morning and evening meals. Recently, the FDA warned that exenatide may increase the risk of severe even fatal pancreatitis (inflammation of the pancreas) and that the drug should be discontinued and not restarted if signs and symptoms of pancreatitis develop (severe abdominal pain, for example). It is not for use in people with type 1 diabetes.

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