Your doctor will check them for redness, cracks, sores, or open wounds. He'll look for weird problems (like overlapping toes); and he'll do a monofilament test. You’ll close your eyes and he'll simply press a piece of nylon to various parts of your foot. If you can’t feel it, you might have nerve damage. He may also tap on your Achilles tendon to see if the nerves on the back of your ankle are in good condition. A clue that they are? Your foot will point downward automatically.
Your doctor will ask you to fast overnight and then drink a sweet liquid with 75 grams of glucose. Two hours later, a sample of your blood will be taken and sent for analysis. The normal levels are less than 140 mg/dL after two hours. If you have a level of 200 mg/dL or higher after two hours, then it means you have diabetes. Prediabetes means having levels at 140 to 199 mg/dL after two hours.5
The earliest oral diabetes drugs were the sulfonylureas. These work by stimulating the pancreas to produce more insulin. The oldest of these drugs still on the market is chlorpropamide (Diabinese), which has been used for more than 50 years. The second-generation sulfonylureas are taken once or twice a day. They include glipizide (Glucotrol, Glucotrol XL), glyburide (Micronase, DiaBeta, Glynase), and glimepiride (Amaryl). 

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This content is provided as a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health. The NIDDK translates and disseminates research findings through its clearinghouses and education programs to increase knowledge and understanding about health and disease among patients, health professionals, and the public. Content produced by the NIDDK is carefully reviewed by NIDDK scientists and other experts.

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Pramlintide is only appropriate for certain people with diabetes who use insulin and are having problems maintaining their blood sugar levels. Because of the potential for severe hypoglycemia with the use of pramlintide is with insulin, adjustments to insulin dosage and more frequent glucose monitoring may be necessary. Insulin and pramlintide should not be mixed in the same syringe.

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You may barely make it to office on time, but that doesn’t mean you skip breakfast. That means you wake up earlier! A healthy breakfast starts your day on the right note. It gives your metabolism the kick-start it needs so that, later in the day, you don’t overeat. Choose healthy breakfast options like oatmeal, eggs with whole-wheat toast or a breakfast smoothie made with fresh fruits and vegetables.
High blood sugar (hyperglycemia). Your blood sugar level can rise for many reasons, including eating too much, being sick or not taking enough glucose-lowering medication. Check your blood sugar level as directed by your doctor, and watch for signs and symptoms of high blood sugar — frequent urination, increased thirst, dry mouth, blurred vision, fatigue and nausea. If you have hyperglycemia, you'll need to adjust your meal plan, medications or both.

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Check your blood sugar level regularly, and watch for signs and symptoms of low blood sugar — sweating, shakiness, weakness, hunger, dizziness, headache, blurred vision, heart palpitations, irritability, slurred speech, drowsiness, confusion, fainting and seizures. Low blood sugar is treated with quickly absorbed carbohydrates, such as fruit juice or glucose tablets.

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